Benzeneacetic acid, α-bromo-4-fluoro-, ethyl ester

Benzeneacetic acid, α-bromo-4-fluoro-, ethyl ester - Names and Identifiers

Name	ethyl bromo(4-fluorophenyl)acetate
Synonyms	Ethyl bromo(4-fluorophenyl)acetate ethyl bromo(4-fluorophenyl)acetate ETHYL BROMO-(4-FLUORO-PHENYL)-ACETATE a-bromo-4-fluorophenylacetic acid ethyl ester BROMO-(4-FLUORO-PHENYL)-ACETIC ACID ETHYL ESTER Benzeneacetic acid, α-bromo-4-fluoro-, ethyl ester 2-Propenoicacid,3-(4-fluorophenyl)-2-methyl-,(4E)- benzeneacetic acid, alpha-bromo-4-fluoro-, ethyl ester Benzeneacetic acid, .alpha.-broMo-4-fluoro-, ethyl ester
CAS	712-52-7
InChI	InChI=1/C10H10BrFO2/c1-2-14-10(13)9(11)7-3-5-8(12)6-4-7/h3-6,9H,2H2,1H3

Benzeneacetic acid, α-bromo-4-fluoro-, ethyl ester - Physico-chemical Properties

Molecular Formula	C10H10BrFO2
Molar Mass	261.09
Density	1.4623 g/cm3
Boling Point	140-143 °C(Press: 13 Torr)
Flash Point	117.3°C
Vapor Presure	0.00685mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.529

Benzeneacetic acid, α-bromo-4-fluoro-, ethyl ester - Introduction

Ethyl bromo(4-fluorophenyl)acetate (ethyl bromo(4-fluorophenyl)acetate) is an organic compound with the chemical formula C10H10BrFO2. It is an ester compound with an ethyl acetate framework and a p-fluorophenyl group and a bromine atom attached to the ethyl acetate framework.

The compound is mainly used as an intermediate in organic synthesis and can be used to synthesize other organic compounds. It is often used to prepare compounds with pharmaceutical activity or as an organic synthesis module in materials science. Its p-fluorophenyl group provides selectivity for oxidation or substitution of substituents or reactive sites.

The method for preparing ethyl bromo(4-fluorophenyl)acetate is generally by reacting p-fluorobenzoic acid and cuprous bromide (CuBr) in ethyl acetate solvent. The reaction is usually carried out at low temperature and with the protection of an inert atmosphere.

Regarding safety information, ethyl bromo(4-fluorophenyl) is acetate an organic bromine compound, which has certain toxicity and irritation. Use should be careful to avoid contact with skin, eyes and respiratory tract. Appropriate protective measures such as gloves, goggles and masks should be taken during handling and storage. In case of accidental exposure or inhalation, medical help should be sought immediately.

Last Update：2024-04-09 20:02:46